Assay Detail
Binding
CHEMBL876147
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for inhibition of AgRP (agouti related protein) binding to MC4 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Expert |
Target
Melanocortin receptor (M1 and M4) (CHEMBL2111423) ↗| Type | SELECTIVITY GROUP |
| Organism | Homo sapiens |
Publication
Piperazinebenzylamines as potent and selective antagonists of the human melanocortin-4 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.28 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL12811 | — | — | 1 | 7.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL12811 | — | IC50 | = | 52.0 | nM | 7.28 |