Assay Detail
Binding
CHEMBL876368
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Binding affinity for isolated C1b domain of protein kinase C-delta
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.32 | 9.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL137386 | — | — | 1 | 9.05 |
| CHEMBL96766 | — | — | 1 | 8.94 |
| CHEMBL187002 | — | — | 1 | 5.84 |
| CHEMBL1169402 | — | — | 1 | 5.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL137386 | — | Ki | = | 0.9 | nM | 9.05 |
| CHEMBL96766 | — | Ki | = | 1.16 | nM | 8.94 |
| CHEMBL187002 | — | Ki | = | 1457.0 | nM | 5.84 |
| CHEMBL1169402 | — | Ki | = | 3473.0 | nM | 5.46 |