Assay Detail
Binding
CHEMBL876410
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration required for inhibition of serine/threonine protein phosphatase calcineurin (CAN)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Protein phosphatase 3 catalytic subunit alpha (CHEMBL4445) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
C32-O-phenalkyl ether derivatives of the immunosuppressant ascomycin: a tether length study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.00 | 8.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL406186 | — | — | 1 | 8.14 |
| CHEMBL263032 | — | — | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL406186 | — | IC50 | = | 7.2 | nM | 8.14 |
| CHEMBL263032 | — | IC50 | = | 14.0 | nM | 7.85 |