Assay Detail
Binding
CHEMBL877290
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Bovine erythrocyte carbonic anhydrase inhibitory activity of the compound.
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Synthesis and physicochemical properties of sulfamate derivatives as topical antiglaucoma agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 7.10 | 7.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL544763 | — | — | 1 | 7.64 |
| CHEMBL545555 | — | — | 1 | 7.38 |
| CHEMBL555867 | — | — | 1 | 7.30 |
| CHEMBL541599 | — | — | 1 | 7.16 |
| CHEMBL542496 | — | — | 1 | 7.14 |
| CHEMBL555738 | — | — | 1 | 7.11 |
| CHEMBL545088 | — | — | 1 | 7.03 |
| CHEMBL553542 | — | — | 1 | 6.92 |
| CHEMBL555771 | — | — | 1 | 6.68 |
| CHEMBL543683 | — | — | 1 | 6.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL544763 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL545555 | — | IC50 | = | 42.0 | nM | 7.38 |
| CHEMBL555867 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL541599 | — | IC50 | = | 69.0 | nM | 7.16 |
| CHEMBL542496 | — | IC50 | = | 72.0 | nM | 7.14 |
| CHEMBL555738 | — | IC50 | = | 77.0 | nM | 7.11 |
| CHEMBL545088 | — | IC50 | = | 94.0 | nM | 7.03 |
| CHEMBL553542 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL555771 | — | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL543683 | — | IC50 | = | 250.0 | nM | 6.60 |