Assay Detail
Binding
CHEMBL877323
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Inhibitory concentration against L-type [Ca2+] channel
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Voltage-gated L-type calcium channel (CHEMBL2095229) ↗| Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
Publication
Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.57 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL20896 | — | — | 1 | 5.57 |
| CHEMBL193988 | — | — | 1 | - |
| CHEMBL2113086 | — | — | 1 | - |
| CHEMBL435886 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL20896 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL193988 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2113086 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL435886 | — | IC50 | > | 10000.0 | nM | - |