Assay Detail
Binding
CHEMBL877676
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity against the cloned human Cannabinoid receptor 1
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.46 | 6.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL277297 | — | — | 1 | 6.44 |
| CHEMBL15150 | ARACHIDONAMIDE | — | 1 | 5.02 |
| CHEMBL161520 | — | — | 1 | 4.91 |
| CHEMBL149859 | LINOLEOYLETHANOLAMIDE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL277297 | — | Ki | = | 364.0 | nM | 6.44 |
| CHEMBL15150 | ARACHIDONAMIDE | Ki | = | 9600.0 | nM | 5.02 |
| CHEMBL161520 | — | Ki | = | 12200.0 | nM | 4.91 |
| CHEMBL149859 | LINOLEOYLETHANOLAMIDE | Ki | > | 41400.0 | nM | - |