Assay Detail
Binding
CHEMBL877816
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Binding affinity towards rat hippocampus GlyT1 transporter expressed in HEK 293 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | HEK293 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Sodium- and chloride-dependent glycine transporter 1 (CHEMBL2337) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
[3H]-(R)-NPTS, a radioligand for the type 1 glycine transporter.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.95 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL26512 | — | — | 1 | 9.10 |
| CHEMBL23390 | — | — | 1 | 8.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL26512 | — | Kd | = | 0.8 | nM | 9.10 |
| CHEMBL23390 | — | Kd | = | 1.6 | nM | 8.80 |