Assay Detail
Functional
CHEMBL878464
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The compound was tested in vitro for inhibition of HIV-1 replication
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 integrase (CHEMBL3471) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
Lamellarin alpha 20-sulfate, an inhibitor of HIV-1 integrase active against HIV-1 virus in cell culture.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.03 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301226 | — | — | 1 | 6.00 |
| CHEMBL430776 | — | — | 1 | 5.10 |
| CHEMBL56784 | — | — | 1 | 4.92 |
| CHEMBL57138 | — | — | 1 | 4.75 |
| CHEMBL297923 | — | — | 1 | 4.70 |
| CHEMBL301410 | — | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301226 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL430776 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL56784 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL57138 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL297923 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL301410 | — | IC50 | = | 20000.0 | nM | 4.70 |