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Assay Detail

CHEMBL878708

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of inositol-trisphosphate phosphorylation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Total synthesis of L-2,2-difluoro-2-deoxy-MYO-inositol 1,4,5-trisphosphate, a potent inhibitor of the enzymes of d-MYO-inositol 1,4,5-trisphosphate metabolism
Sawyer DA, Potter BV
Bioorg Med Chem Lett (1991) 1 : 705 -710
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.94 4.94

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1161466 1 4.94

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1161466 Ki = 11500.0 nM 4.94