Assay Detail
Functional
CHEMBL878895
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Inhibitory concentration against human oral cancer cell line (KB) using tetrazolium dye reduction assay (MTT)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Structure-activity and crystallographic analysis of benzophenone derivatives-the potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.80 | 8.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL67 | COMBRETASTATIN A4 | -1.0 | 1 | 8.21 |
| CHEMBL9011 | — | — | 1 | 7.59 |
| CHEMBL9309 | — | — | 1 | 7.42 |
| CHEMBL8953 | — | — | 1 | 7.04 |
| CHEMBL276625 | PHENSTATIN | — | 1 | 6.89 |
| CHEMBL9241 | — | — | 1 | 5.26 |
| CHEMBL8939 | — | — | 1 | 5.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL67 | COMBRETASTATIN A4 | IC50 | = | 6.2 | nM | 8.21 |
| CHEMBL9011 | — | IC50 | = | 25.8 | nM | 7.59 |
| CHEMBL9309 | — | IC50 | = | 38.5 | nM | 7.42 |
| CHEMBL8953 | — | IC50 | = | 90.4 | nM | 7.04 |
| CHEMBL276625 | PHENSTATIN | IC50 | = | 128.7 | nM | 6.89 |
| CHEMBL9241 | — | IC50 | = | 5462.2 | nM | 5.26 |
| CHEMBL8939 | — | IC50 | = | 6080.8 | nM | 5.22 |