Assay Detail
Functional
CHEMBL879147
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity for Human PPAR delta receptor in transcriptional activation assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Peroxisome proliferator-activated receptor delta (CHEMBL3979) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The PPARs: from orphan receptors to drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 5.88 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278994 | L-796449 | — | 1 | 8.10 |
| CHEMBL435278 | — | — | 1 | 6.72 |
| CHEMBL153057 | — | — | 1 | 6.28 |
| CHEMBL278590 | GSK-9578 | — | 1 | 5.85 |
| CHEMBL24458 | — | — | 1 | 5.04 |
| CHEMBL264374 | BEZAFIBRATE | 3.0 | 1 | 4.70 |
| CHEMBL295416 | PIRINIXIC ACID | 2.0 | 1 | 4.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278994 | L-796449 | EC50 | = | 7.9 | nM | 8.10 |
| CHEMBL435278 | — | EC50 | = | 190.0 | nM | 6.72 |
| CHEMBL153057 | — | EC50 | = | 530.0 | nM | 6.28 |
| CHEMBL278590 | GSK-9578 | EC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL24458 | — | EC50 | = | 9100.0 | nM | 5.04 |
| CHEMBL264374 | BEZAFIBRATE | EC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL295416 | PIRINIXIC ACID | EC50 | = | 35000.0 | nM | 4.46 |