Assay Detail
Binding
CHEMBL879244
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Transcriptional activation of Retinoic acid receptor RAR gamma
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Identification of the first retinoid X, receptor homodimer antagonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.14 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL111589 | — | — | 1 | 7.77 |
| CHEMBL109847 | — | — | 1 | 6.92 |
| CHEMBL109581 | — | — | 1 | 6.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL111589 | — | EC50 | = | 17.0 | nM | 7.77 |
| CHEMBL109847 | — | EC50 | = | 121.0 | nM | 6.92 |
| CHEMBL109581 | — | EC50 | = | 192.0 | nM | 6.72 |