Assay Detail

CHEMBL879445

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Growth inhibitory activity of compound on L1210 cells after 48 hours

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

L1210 (CHEMBL386) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

L1210 (CHEMBL386) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target L1210

CHEMBL386

Anchored from Assay target.

Protein identity L1210

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Rattus norvegicus
Cell Type	L1210
Confidence	1 — Organism
Curated By	Intermediate

Target

L1210 (CHEMBL386) ↗

Type	CELL-LINE
Organism	Mus musculus

Publication

Metabolically programmed polyamine analogue antidiarrheals.

Bergeron RJ, Yao GW, Yao H, Weimar WR, Sninsky CA, Raisler B, Feng Y, Wu Q, Gao F.
J Med Chem (1996) 39 : 2461 -2471
PubMed 8691443 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.70	6.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL77101	DIETHYLHOMOSPERMINE	1.0	1	6.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL77101	DIETHYLHOMOSPERMINE	IC50	=	200.0	nM	6.70