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Assay Detail

CHEMBL880595

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Effect against trans-activation responsive RNA-binding protein at pH 7.4 (50 mM Tris-HCl and 20 mM KCl) in fluorimetric competition assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Neamine dimers targeting the HIV-1 TAR RNA.
Riguet E, Désiré J, Boden O, Ludwig V, Göbel M, Bailly C, Décout JL.
Bioorg Med Chem Lett (2005) 15 : 4651 -4655
PubMed 16153833 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL427409 NEAMINE 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL427409 NEAMINE IC50 = 10000.0 nM 5.00