Assay Detail
Functional
CHEMBL880718
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Compound was evaluated for the inhibition of HUVEC-induced LDL oxidation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HUVEC |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design and synthesis of new hypocholesterolemic organosilanes with antioxidant properties
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.73 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL434507 | — | — | 1 | 5.16 |
| CHEMBL108692 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL434507 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL108692 | — | IC50 | = | 50000.0 | nM | 4.30 |