Assay Detail
Binding
CHEMBL880877
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Dissociation constant for Retinoic acid receptor gamma
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Ligand recognition by RAR and RXR receptors: binding and selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 8.14 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38 | TRETINOIN | 4.0 | 1 | 9.70 |
| CHEMBL705 | ALITRETINOIN | 4.0 | 1 | 9.10 |
| CHEMBL275311 | — | — | 1 | 7.58 |
| CHEMBL32505 | — | — | 1 | 6.19 |
| CHEMBL75133 | IRX-4204 | 2.0 | 1 | - |
| CHEMBL308377 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38 | TRETINOIN | Kd | = | 0.2 | nM | 9.70 |
| CHEMBL705 | ALITRETINOIN | Kd | = | 0.8 | nM | 9.10 |
| CHEMBL275311 | — | Kd | = | 26.0 | nM | 7.58 |
| CHEMBL32505 | — | Kd | = | 645.0 | nM | 6.19 |
| CHEMBL75133 | IRX-4204 | Kd | > | 30000.0 | nM | - |
| CHEMBL308377 | — | Kd | > | 10000.0 | nM | - |