Assay Detail
Binding
CHEMBL881208
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Binding affinity towards peroxisome proliferator activated receptor gamma
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Designed multiple ligands. An emerging drug discovery paradigm.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 6.07 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL86658 | — | — | 1 | 6.77 |
| CHEMBL328455 | — | — | 1 | 6.52 |
| CHEMBL24458 | — | — | 1 | 6.48 |
| CHEMBL314483 | — | — | 1 | 5.57 |
| CHEMBL194411 | — | — | 1 | 5.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL86658 | — | Kd | = | 170.0 | nM | 6.77 |
| CHEMBL328455 | — | Kd | = | 300.0 | nM | 6.52 |
| CHEMBL24458 | — | Kd | = | 330.0 | nM | 6.48 |
| CHEMBL314483 | — | Kd | = | 2700.0 | nM | 5.57 |
| CHEMBL194411 | — | Kd | = | 9800.0 | nM | 5.01 |