Assay Detail
Binding
CHEMBL881230
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against 5-hydroxytryptamine 2 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Designed multiple ligands. An emerging drug discovery paradigm.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.10 | 9.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL708 | ZIPRASIDONE | 4.0 | 1 | 9.38 |
| CHEMBL54786 | — | — | 1 | 7.70 |
| CHEMBL277120 | — | — | 1 | 7.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL708 | ZIPRASIDONE | IC50 | = | 0.42 | nM | 9.38 |
| CHEMBL54786 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL277120 | — | IC50 | = | 62.0 | nM | 7.21 |