Assay Detail
Binding
CHEMBL881489
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against 5-hydroxytryptamine 2A receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
6-Acylamino-2-aminoquinolines as potent melanin-concentrating hormone 1 receptor antagonists. Identification, structure-activity relationship, and investigation of binding mode.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.47 | 9.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL194837 | — | — | 1 | 9.21 |
| CHEMBL189118 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL194837 | — | IC50 | = | 0.61 | nM | 9.21 |
| CHEMBL189118 | — | IC50 | = | 1900.0 | nM | 5.72 |