Assay Detail
Binding
CHEMBL882278
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Inhibitory activity against Tissue type plasminogen activator
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Development of irreversible diphenyl phosphonate inhibitors for urokinase plasminogen activator.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.85 | 4.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL80844 | — | — | 1 | 4.85 |
| CHEMBL945 | AMILORIDE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL80844 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL945 | AMILORIDE | IC50 | >> | 250000.0 | nM | - |