Assay Detail
Functional
CHEMBL882650
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition constant was determined for the facilitated transport of [3N]-thymidine by murine erythrocyte NBMPR-sensitive nucleoside transporter.
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and antiviral and cytotoxic activity of iodohydrin and iodomethoxy derivatives of 5-vinyl-2'-deoxyuridines, 2'-fluoro-2'-deoxyuridine, and uridine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 4.53 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL223205 | — | — | 1 | 4.60 |
| CHEMBL3142952 | — | — | 1 | 4.46 |
| CHEMBL3143527 | — | — | 1 | - |
| CHEMBL3143529 | — | — | 1 | - |
| CHEMBL3143532 | — | — | 1 | - |
| CHEMBL161699 | — | — | 1 | - |
| CHEMBL353955 | DEOXYURIDINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL223205 | — | Ki | = | 25000.0 | nM | 4.60 |
| CHEMBL3142952 | — | Ki | = | 35000.0 | nM | 4.46 |
| CHEMBL3143527 | — | Ki | = | 610000.0 | nM | - |
| CHEMBL3143529 | — | Ki | = | 155000.0 | nM | - |
| CHEMBL3143532 | — | Ki | = | 8000000.0 | nM | - |
| CHEMBL161699 | — | Ki | = | 220000.0 | nM | - |
| CHEMBL353955 | DEOXYURIDINE | Ki | = | 125000.0 | nM | - |