Assay Detail
Binding
CHEMBL883243
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was evaluated for intrinsic activity against human cloned 5-hydroxytryptamine 1B receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Arylpiperazide derivatives of phenylpiperazines as a new class of potent and selective 5-HT1B receptor antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.36 | 8.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL323986 | — | — | 1 | 8.72 |
| CHEMBL111302 | — | — | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL323986 | — | EC50 | = | 1.9 | nM | 8.72 |
| CHEMBL111302 | — | EC50 | = | 10.0 | nM | 8.00 |