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Assay Detail

CHEMBL883280

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity was evaluated against Angiotensin II receptor, type 1 in bovine adrenal membrane
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Type-1 angiotensin II receptor (CHEMBL3374)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.
Wexler RR, Greenlee WJ, Irvin JD, Goldberg MR, Prendergast K, Smith RD, Timmermans PB.
J Med Chem (1996) 39 : 625 -656
PubMed 8576904 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.60 6.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL48602 1 6.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL48602 IC50 = 250.0 nM 6.60