Assay Detail
Binding
CHEMBL884031
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Inhibitory activity towards Alpha-glucosidase from Baker yeast (isomaltase)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.18 | 4.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL313295 | — | — | 1 | 4.19 |
| CHEMBL2206827 | — | — | 1 | 4.16 |
| CHEMBL2206826 | — | — | 1 | - |
| CHEMBL82895 | — | — | 1 | - |
| CHEMBL84940 | — | — | 1 | - |
| CHEMBL2115197 | — | — | 1 | - |
| CHEMBL84272 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL313295 | — | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL2206827 | — | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL2206826 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL82895 | — | IC50 | = | 120000.0 | nM | - |
| CHEMBL84940 | — | IC50 | = | 170000.0 | nM | - |
| CHEMBL2115197 | — | IC50 | = | 330000.0 | nM | - |
| CHEMBL84272 | — | IC50 | = | 120000.0 | nM | - |