Assay Detail
Functional
CHEMBL884064
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The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 3 (P2X3) at 10 uM, expressed in Xenopus oocytes
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | Oocyte |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Purine and pyrimidine (P2) receptors as drug targets.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.95 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL337062 | — | — | 1 | 7.77 |
| CHEMBL69234 | — | — | 1 | 6.62 |
| CHEMBL130094 | — | — | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL337062 | — | EC50 | = | 17.0 | nM | 7.77 |
| CHEMBL69234 | — | EC50 | = | 240.0 | nM | 6.62 |
| CHEMBL130094 | — | EC50 | = | 350.0 | nM | 6.46 |