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Assay Detail

CHEMBL884356

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for its inhibitory activity against cyclin-dependent kinase 5
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Cyclin-dependent kinase 5 (CHEMBL4036)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

3D-QSAR CoMFA on cyclin-dependent kinase inhibitors.
Ducrot P, Legraverend M, Grierson DS.
J Med Chem (2000) 43 : 4098 -4108
PubMed 11063606 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.35 6.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL422759 1 6.40
CHEMBL25840 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL422759 IC50 = 400.0 nM 6.40
CHEMBL25840 IC50 = 500.0 nM 6.30