Assay Detail
Binding
CHEMBL884444
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested in vitro for its binding affinity towards human Dopamine receptor D2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
New (sulfonyloxy)piperazinyldibenzazepines as potential atypical antipsychotics: chemistry and pharmacological evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.27 | 7.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL831 | LOXAPINE | 4.0 | 1 | 7.27 |
| CHEMBL306474 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL831 | LOXAPINE | IC50 | = | 54.0 | nM | 7.27 |
| CHEMBL306474 | — | IC50 | > | 1000.0 | nM | - |