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Assay Detail

CHEMBL884735

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Binding
Inhibitory constant against the protein kinase A
6
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

cAMP-dependent protein kinase (PKA) (CHEMBL2094138)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Joys of molecules. 2. Endeavors in chemical biology and medicinal chemistry.
Nicolaou KC.
J Med Chem (2005) 48 : 5613 -5638
PubMed 16134928 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 6 8.40 8.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL365598 2 8.47
CHEMBL193697 2 8.41
CHEMBL60254 BALANOL 2 8.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL365598 Ki = 3.4 nM 8.47
CHEMBL365598 Ki = 3.4 nM 8.47
CHEMBL193697 Ki = 3.9 nM 8.41
CHEMBL193697 Ki = 3.9 nM 8.41
CHEMBL60254 BALANOL Ki = 4.7 nM 8.33
CHEMBL60254 BALANOL Ki = 4.7 nM 8.33