Assay Detail
Functional
CHEMBL885030
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Inhibitory activity against Coxsackievirus B4 using plaque reduction assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Coxsackievirus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antipicornavirus activity of (R)- and (S)-1-[5-(4'-chlorobiphenyl-4-yloxy)-3-methylpentyl]-3-pyridin-4-yl-imidazolidin-2-one.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.83 | 5.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL194616 | — | — | 1 | 5.90 |
| CHEMBL45426 | — | — | 1 | 5.89 |
| CHEMBL372209 | — | — | 1 | 5.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL194616 | — | IC50 | = | 1250.0 | nM | 5.90 |
| CHEMBL45426 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL372209 | — | IC50 | = | 2050.0 | nM | 5.69 |