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Assay Detail

CHEMBL885035

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory activity against Coxsackievirus A10 using plaque reduction assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Coxsackievirus
Confidence 1 — Organism
Curated By Intermediate

Target

Coxsackievirus (CHEMBL613750)
Type ORGANISM
Organism Coxsackievirus

Publication

Synthesis and antipicornavirus activity of (R)- and (S)-1-[5-(4'-chlorobiphenyl-4-yloxy)-3-methylpentyl]-3-pyridin-4-yl-imidazolidin-2-one.
Chern JH, Chang CS, Tai CL, Lee YC, Lee CC, Kang IJ, Lee CY, Shih SR.
Bioorg Med Chem Lett (2005) 15 : 4206 -4211
PubMed 16054357 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.88 5.88

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL194616 1 5.88
CHEMBL45426 1 -
CHEMBL372209 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL194616 IC50 = 1320.0 nM 5.88
CHEMBL45426 IC50 > 25000.0 nM -
CHEMBL372209 IC50 > 25000.0 nM -