Assay Detail
Binding
CHEMBL885140
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]oxytocin from human V2 vasopressin receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists. 2. Synthesis, chirality, and pharmacokinetics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.20 | 6.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL196478 | — | — | 1 | 6.20 |
| CHEMBL197793 | — | — | 1 | - |
| CHEMBL196603 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL196478 | — | Ki | = | 630.96 | nM | 6.20 |
| CHEMBL197793 | — | Ki | < | 1258.93 | nM | - |
| CHEMBL196603 | — | Ki | < | 79432.82 | nM | - |