Assay Detail
Functional
CHEMBL885789
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Induction of bioluminescence in Vibrio harveyi after 4 hrs by beta-Gal reporter gene assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vibrio harveyi |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Ac2-DPD, the bis-(O)-acetylated derivative of 4,5-dihydroxy-2,3-pentanedione (DPD) is a convenient stable precursor of bacterial quorum sensing autoinducer AI-2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.59 | 5.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL393458 | — | — | 1 | 5.68 |
| CHEMBL247567 | — | — | 1 | 5.62 |
| CHEMBL193493 | — | — | 1 | 5.58 |
| CHEMBL247773 | — | — | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL393458 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL247567 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL193493 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL247773 | — | IC50 | = | 3300.0 | nM | 5.48 |