Assay Detail
Binding
CHEMBL885903
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Inhibition of VEGFR2 by [32P]ATP-competitive radioassay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Vascular endothelial growth factor receptor 2 (CHEMBL279) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
ortho-Substituted azoles as selective and dual inhibitors of VEGF receptors 1 and 2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.76 | 9.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL238737 | — | — | 1 | 9.80 |
| CHEMBL401040 | — | — | 1 | 9.77 |
| CHEMBL393779 | — | — | 1 | 9.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL238737 | — | Ki | = | 0.16 | nM | 9.80 |
| CHEMBL401040 | — | Ki | = | 0.17 | nM | 9.77 |
| CHEMBL393779 | — | Ki | = | 0.2 | nM | 9.70 |