Assay Detail
Binding
CHEMBL886031
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of temperature-induced tubulin polymerization of calf brain
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antimitotic activities of 2-phenylindole-3-carbaldehydes in human breast cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.68 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL145872 | — | — | 1 | 5.82 |
| CHEMBL228680 | — | — | 1 | 5.75 |
| CHEMBL148029 | — | — | 1 | 5.75 |
| CHEMBL147487 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL145872 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL228680 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL148029 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL147487 | — | IC50 | = | 4000.0 | nM | 5.40 |