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Assay Detail

CHEMBL886243

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of EBV DNA polymerase by T7 quick-coupled transcription-translation system
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human gammaherpesvirus 4
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.
Schnute ME, Anderson DJ, Brideau RJ, Ciske FL, Collier SA, Cudahy MM, Eggen M, Genin MJ, Hopkins TA, Judge TM, Kim EJ, Knechtel ML, Nair SK, Nieman JA, Oien NL, Scott A, Tanis SP, Vaillancourt VA, Wathen MW, Wieber JL.
Bioorg Med Chem Lett (2007) 17 : 3349 -3353
PubMed 17434304 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.16 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL248161 1 7.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL248161 IC50 = 70.0 nM 7.16