Assay Detail
Binding
CHEMBL886480
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Activity at RXR-PPARgamma heterodimer in primary human preadipocytes assessed as induction of adipocytes fatty acid binding protein by bDNA assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
RXR-LXR heterodimer modulators for the potential treatment of dyslipidemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 6.88 | 6.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL247005 | — | — | 1 | 6.90 |
| CHEMBL246629 | — | — | 1 | 6.88 |
| CHEMBL248415 | — | — | 1 | 6.86 |
| CHEMBL248191 | — | — | 1 | - |
| CHEMBL247819 | — | — | 1 | - |
| CHEMBL400557 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL247005 | — | EC50 | = | 126.0 | nM | 6.90 |
| CHEMBL246629 | — | EC50 | = | 131.0 | nM | 6.88 |
| CHEMBL248415 | — | EC50 | = | 139.0 | nM | 6.86 |
| CHEMBL248191 | — | EC50 | > | 3000.0 | nM | - |
| CHEMBL247819 | — | EC50 | > | 3000.0 | nM | - |
| CHEMBL400557 | — | EC50 | > | 3000.0 | nM | - |