Assay Detail
Functional
CHEMBL886595
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Cytotoxicity against CD70 positive Caki1 cells assessed as cell viability after 96 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CAKI-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Minor groove binder antibody conjugates employing a water soluble beta-glucuronide linker.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.15 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL117142 | — | — | 1 | 9.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL117142 | — | IC50 | = | 0.7 | nM | 9.15 |