Assay Detail
Binding
CHEMBL887390
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]naltrindole from human delta opioid receptors expressed in CHO cell membrane
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
High-affinity carbamate analogues of morphinan at opioid receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 13 | 8.03 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL397035 | — | — | 1 | 8.80 |
| CHEMBL49269 | CYCLORPHAN | — | 1 | 8.72 |
| CHEMBL263096 | — | — | 1 | 8.57 |
| CHEMBL427862 | — | — | 1 | 8.55 |
| CHEMBL242048 | — | — | 1 | 8.41 |
| CHEMBL592 | LEVORPHANOL | 4.0 | 1 | 8.38 |
| CHEMBL301160 | BUTORPHAN | — | 1 | 8.23 |
| CHEMBL394624 | — | — | 1 | 7.82 |
| CHEMBL242047 | — | — | 1 | 7.57 |
| CHEMBL242046 | — | — | 1 | 7.52 |
| CHEMBL241824 | — | — | 1 | 7.38 |
| CHEMBL245049 | — | — | 1 | 7.28 |
| CHEMBL241823 | — | — | 1 | 7.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL397035 | — | Ki | = | 1.6 | nM | 8.80 |
| CHEMBL49269 | CYCLORPHAN | Ki | = | 1.9 | nM | 8.72 |
| CHEMBL263096 | — | Ki | = | 2.7 | nM | 8.57 |
| CHEMBL427862 | — | Ki | = | 2.8 | nM | 8.55 |
| CHEMBL242048 | — | Ki | = | 3.9 | nM | 8.41 |
| CHEMBL592 | LEVORPHANOL | Ki | = | 4.2 | nM | 8.38 |
| CHEMBL301160 | BUTORPHAN | Ki | = | 5.9 | nM | 8.23 |
| CHEMBL394624 | — | Ki | = | 15.0 | nM | 7.82 |
| CHEMBL242047 | — | Ki | = | 27.0 | nM | 7.57 |
| CHEMBL242046 | — | Ki | = | 30.0 | nM | 7.52 |
| CHEMBL241824 | — | Ki | = | 42.0 | nM | 7.38 |
| CHEMBL245049 | — | Ki | = | 53.0 | nM | 7.28 |
| CHEMBL241823 | — | Ki | = | 78.0 | nM | 7.11 |