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Assay Detail

CHEMBL888740

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human PRMT1 by TRF assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Protein arginine N-methyltransferase 1 (CHEMBL5524)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A novel arginine methyltransferase inhibitor with cellular activity.
Spannhoff A, Machmur R, Heinke R, Trojer P, Bauer I, Brosch G, Schüle R, Hanefeld W, Sippl W, Jung M.
Bioorg Med Chem Lett (2007) 17 : 4150 -4153
PubMed 17570663 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.26 4.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL61824 1 4.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL61824 IC50 = 55400.0 nM 4.26