Assay Detail
Binding
CHEMBL888757
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Enhancement of [3H]flunitrazepam binding to BZ-site of GABAA receptor in Sprague-Dawley rat cortex membrane
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Enaminone amides as novel orally active GABAA receptor modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.72 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL387622 | — | — | 1 | 8.22 |
| CHEMBL229257 | — | — | 1 | 7.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL387622 | — | EC50 | = | 6.0 | nM | 8.22 |
| CHEMBL229257 | — | EC50 | = | 60.0 | nM | 7.22 |