Assay Detail
Functional
CHEMBL889105
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Inhibition of chemotaxis in human MCP1 monocytes
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
3-Amino-1-alkyl-cyclopentane carboxamides as small molecule antagonists of the human and murine CC chemokine receptor 2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.65 | 9.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL230933 | — | — | 1 | 9.82 |
| CHEMBL437359 | — | — | 1 | 9.64 |
| CHEMBL231039 | — | — | 1 | 9.49 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL230933 | — | IC50 | = | 0.15 | nM | 9.82 |
| CHEMBL437359 | — | IC50 | = | 0.23 | nM | 9.64 |
| CHEMBL231039 | — | IC50 | = | 0.32 | nM | 9.49 |