Assay Detail
Binding
CHEMBL889333
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Inhibition of rat F10a
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.45 | 10.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL427421 | — | — | 1 | 10.22 |
| CHEMBL173994 | — | — | 1 | 9.54 |
| CHEMBL227222 | — | — | 1 | 8.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL427421 | — | Ki | = | 0.06 | nM | 10.22 |
| CHEMBL173994 | — | Ki | = | 0.29 | nM | 9.54 |
| CHEMBL227222 | — | Ki | = | 2.5 | nM | 8.60 |