Assay Detail
Binding
CHEMBL889366
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Inhibition of HIV protease
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and antiviral property of allophenylnorstatine-based HIV protease inhibitors incorporating D-cysteine derivatives as P2/P3 moieties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 9.86 | 10.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL414774 | — | — | 1 | 10.08 |
| CHEMBL396466 | — | — | 1 | 10.07 |
| CHEMBL387835 | — | — | 1 | 10.05 |
| CHEMBL267659 | — | — | 1 | 10.05 |
| CHEMBL230484 | — | — | 1 | 9.74 |
| CHEMBL396462 | — | — | 1 | 9.59 |
| CHEMBL230270 | — | — | 1 | 9.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL414774 | — | IC50 | = | 0.083 | nM | 10.08 |
| CHEMBL396466 | — | IC50 | = | 0.086 | nM | 10.07 |
| CHEMBL387835 | — | IC50 | = | 0.09 | nM | 10.05 |
| CHEMBL267659 | — | IC50 | = | 0.09 | nM | 10.05 |
| CHEMBL230484 | — | IC50 | = | 0.18 | nM | 9.74 |
| CHEMBL396462 | — | IC50 | = | 0.26 | nM | 9.59 |
| CHEMBL230270 | — | IC50 | = | 0.34 | nM | 9.47 |