Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL889770

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against BVDV in MDBK cells
ChEMBL ↗
56
Total Activities
56
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Bovine viral diarrhea virus 1
Cell Type MDBK
Confidence 1 — Organism
Curated By Intermediate

Target

Bovine viral diarrhea virus 1 (CHEMBL612571) ↗
Type ORGANISM
Organism Bovine viral diarrhea virus 1

Publication

Antiviral 2,5-disubstituted imidazo[4,5-c]pyridines: further optimization of anti-hepatitis C virus activity.
Puerstinger G, Paeshuyse J, Heinrich S, Mohr J, Schraffl N, De Clercq E, Neyts J.
Bioorg Med Chem Lett (2007) 17 : 5111 -5114
PubMed 17656093 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 56 6.37 7.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL390395 — — 1 7.30
CHEMBL395802 — — 1 7.30
CHEMBL243316 — — 1 7.10
CHEMBL397219 — — 1 7.00
CHEMBL428396 — — 1 6.96
CHEMBL398229 — — 1 6.92
CHEMBL243535 — — 1 6.92
CHEMBL242913 — — 1 6.85
CHEMBL242029 — — 1 6.80
CHEMBL242912 — — 1 6.75
CHEMBL390260 — — 1 6.75
CHEMBL395507 — — 1 6.70
CHEMBL396486 — — 1 6.70
CHEMBL242700 — — 1 6.64
CHEMBL243315 — — 1 6.62
CHEMBL390215 — — 1 6.60
CHEMBL244810 — — 1 6.60
CHEMBL243764 — — 1 6.60
CHEMBL440224 — — 1 6.57
CHEMBL242270 — — 1 6.57
CHEMBL396485 — — 1 6.55
CHEMBL242269 — — 1 6.54
CHEMBL242238 — — 1 6.54
CHEMBL242239 — — 1 6.54
CHEMBL397265 — — 1 6.50
CHEMBL395315 — — 1 6.50
CHEMBL243972 — — 1 6.44
CHEMBL242699 — — 1 6.43
CHEMBL398216 — — 1 6.42
CHEMBL242698 — — 1 6.42

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL390395 — EC50 = 50.0 nM 7.30
CHEMBL395802 — EC50 = 50.0 nM 7.30
CHEMBL243316 — EC50 = 80.0 nM 7.10
CHEMBL397219 — EC50 = 100.0 nM 7.00
CHEMBL428396 — EC50 = 110.0 nM 6.96
CHEMBL398229 — EC50 = 120.0 nM 6.92
CHEMBL243535 — EC50 = 120.0 nM 6.92
CHEMBL242913 — EC50 = 140.0 nM 6.85
CHEMBL242029 — EC50 = 160.0 nM 6.80
CHEMBL242912 — EC50 = 180.0 nM 6.75
CHEMBL390260 — EC50 = 180.0 nM 6.75
CHEMBL395507 — EC50 = 200.0 nM 6.70
CHEMBL396486 — EC50 = 200.0 nM 6.70
CHEMBL242700 — EC50 = 230.0 nM 6.64
CHEMBL243315 — EC50 = 240.0 nM 6.62
CHEMBL390215 — EC50 = 250.0 nM 6.60
CHEMBL243764 — EC50 = 250.0 nM 6.60
CHEMBL244810 — EC50 = 250.0 nM 6.60
CHEMBL440224 — EC50 = 270.0 nM 6.57
CHEMBL242270 — EC50 = 270.0 nM 6.57
CHEMBL396485 — EC50 = 280.0 nM 6.55
CHEMBL242269 — EC50 = 290.0 nM 6.54
CHEMBL242238 — EC50 = 290.0 nM 6.54
CHEMBL242239 — EC50 = 290.0 nM 6.54
CHEMBL395315 — EC50 = 320.0 nM 6.50
CHEMBL397265 — EC50 = 320.0 nM 6.50
CHEMBL243972 — EC50 = 360.0 nM 6.44
CHEMBL242699 — EC50 = 370.0 nM 6.43
CHEMBL398216 — EC50 = 380.0 nM 6.42
CHEMBL242698 — EC50 = 380.0 nM 6.42
CHEMBL243546 — EC50 = 400.0 nM 6.40
CHEMBL390396 — EC50 = 440.0 nM 6.36
CHEMBL388706 — EC50 = 480.0 nM 6.32
CHEMBL245050 — EC50 = 490.0 nM 6.31
CHEMBL388705 — EC50 = 500.0 nM 6.30
CHEMBL243534 — EC50 = 530.0 nM 6.28
CHEMBL428043 — EC50 = 520.0 nM 6.28
CHEMBL245275 — EC50 = 560.0 nM 6.25
CHEMBL394364 — EC50 = 600.0 nM 6.22
CHEMBL243785 — EC50 = 610.0 nM 6.21
CHEMBL439198 — EC50 = 670.0 nM 6.17
CHEMBL243973 — EC50 = 680.0 nM 6.17
CHEMBL242483 — EC50 = 690.0 nM 6.16
CHEMBL245026 — EC50 = 690.0 nM 6.16
CHEMBL388232 — EC50 = 710.0 nM 6.15
CHEMBL242485 — EC50 = 720.0 nM 6.14
CHEMBL242911 — EC50 = 720.0 nM 6.14
CHEMBL390397 — EC50 = 800.0 nM 6.10
CHEMBL388021 — EC50 = 830.0 nM 6.08
CHEMBL395550 — EC50 = 1700.0 nM 5.77