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Assay Detail

CHEMBL889941

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of class I FBA
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

New competitive inhibitors of cytosolic (NADH-dependent) rabbit muscle glycerophosphate dehydrogenase.
Fonvielle M, Therisod H, Hemery M, Therisod M.
Bioorg Med Chem Lett (2007) 17 : 410 -413
PubMed 17088060 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 6 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL371668 PHOSPHOGLYCOLOHYDROXAMATE 1 6.00
CHEMBL195520 PHOSPHORIC ACID MONOHYDRAZINOCARBONYLMETHYL ESTER 1 -
CHEMBL195976 1 -
CHEMBL196442 1 -
CHEMBL390655 1 -
CHEMBL1161997 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL371668 PHOSPHOGLYCOLOHYDROXAMATE Ki = 1000.0 nM 6.00
CHEMBL195520 PHOSPHORIC ACID MONOHYDRAZINOCARBONYLMETHYL ESTER Ki = 370000.0 nM -
CHEMBL195976 Ki > 1000000.0 nM -
CHEMBL196442 Ki > 500000.0 nM -
CHEMBL390655 Ki = 9000000.0 nM -
CHEMBL1161997 Ki = 180000.0 nM -