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Assay Detail

CHEMBL891360

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Functional
Antiproliferative activity against human SK-N-MC cells by MTT assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SK-N-MC
Confidence 1 — Organism
Curated By Autocuration

Target

SK-N-MC (CHEMBL614163)
Type CELL-LINE
Organism Homo sapiens

Publication

Investigating biological activity spectrum for novel quinoline analogues.
Musiol R, Jampilek J, Kralova K, Richardson DR, Kalinowski D, Podeszwa B, Finster J, Niedbala H, Palka A, Polanski J.
Bioorg Med Chem (2007) 15 : 1280 -1288
PubMed 17142046 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 13 6.31 6.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL231616 TRIAPINE 3.0 1 6.51
CHEMBL241908 1 6.11
CHEMBL241898 1 -
CHEMBL242547 1 -
CHEMBL242546 1 -
CHEMBL202312 1 -
CHEMBL202369 1 -
CHEMBL397907 1 -
CHEMBL427867 1 -
CHEMBL395092 1 -
CHEMBL242110 1 -
CHEMBL242108 1 -
CHEMBL242107 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL231616 TRIAPINE IC50 = 310.0 nM 6.51
CHEMBL241908 IC50 = 770.0 nM 6.11
CHEMBL241898 IC50 > 6250.0 nM -
CHEMBL242547 IC50 > 6250.0 nM -
CHEMBL242546 IC50 > 6250.0 nM -
CHEMBL202312 IC50 > 6250.0 nM -
CHEMBL202369 IC50 > 6250.0 nM -
CHEMBL397907 IC50 > 6250.0 nM -
CHEMBL427867 IC50 > 6250.0 nM -
CHEMBL395092 IC50 > 6250.0 nM -
CHEMBL242110 IC50 > 6250.0 nM -
CHEMBL242108 IC50 > 6250.0 nM -
CHEMBL242107 IC50 > 6250.0 nM -