Assay Detail
Binding
CHEMBL892537
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Inhibition of GSKp1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Synthesis and activity of quinolinyl-methylene-thiazolinones as potent and selective cyclin-dependent kinase 1 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.30 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL393929 | — | — | 1 | 6.30 |
| CHEMBL396377 | — | — | 1 | - |
| CHEMBL235345 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL393929 | — | Ki | = | 500.0 | nM | 6.30 |
| CHEMBL396377 | — | Ki | > | 2000.0 | nM | - |
| CHEMBL235345 | — | Ki | > | 2000.0 | nM | - |