Assay Detail
Binding
CHEMBL893244
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Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membrane
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 11 | 7.22 | 8.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL49269 | CYCLORPHAN | — | 1 | 8.72 |
| CHEMBL301160 | BUTORPHAN | — | 1 | 8.23 |
| CHEMBL242968 | — | — | 1 | 7.64 |
| CHEMBL242756 | — | — | 1 | 7.54 |
| CHEMBL428038 | — | — | 1 | 7.30 |
| CHEMBL299220 | — | — | 1 | 6.82 |
| CHEMBL394573 | — | — | 1 | 6.80 |
| CHEMBL49143 | — | — | 1 | 6.75 |
| CHEMBL390866 | — | — | 1 | 6.64 |
| CHEMBL243195 | — | — | 1 | 6.57 |
| CHEMBL390912 | — | — | 1 | 6.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL49269 | CYCLORPHAN | Ki | = | 1.9 | nM | 8.72 |
| CHEMBL301160 | BUTORPHAN | Ki | = | 5.9 | nM | 8.23 |
| CHEMBL242968 | — | Ki | = | 23.0 | nM | 7.64 |
| CHEMBL242756 | — | Ki | = | 29.0 | nM | 7.54 |
| CHEMBL428038 | — | Ki | = | 50.0 | nM | 7.30 |
| CHEMBL299220 | — | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL394573 | — | Ki | = | 160.0 | nM | 6.80 |
| CHEMBL49143 | — | Ki | = | 180.0 | nM | 6.75 |
| CHEMBL390866 | — | Ki | = | 230.0 | nM | 6.64 |
| CHEMBL243195 | — | Ki | = | 270.0 | nM | 6.57 |
| CHEMBL390912 | — | Ki | = | 360.0 | nM | 6.44 |