Assay Detail
Binding
CHEMBL893285
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Inhibition of wild type HIV reverse transcriptase in PBM cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus |
| Cell Type | PBM |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of 2'-substituted cyclobutyl nucleosides and nucleotides as potential anti-HIV agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.18 | 5.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1230 | LAMIVUDINE TRIPHOSPHATE | -1.0 | 1 | 5.19 |
| CHEMBL397094 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1230 | LAMIVUDINE TRIPHOSPHATE | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL397094 | — | IC50 | = | 6900.0 | nM | 5.16 |