Assay Detail
Functional
CHEMBL893663
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Growth inhibition of TK10 cells by sulforhodamine assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | TK-10 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthetic chalcones, flavanones, and flavones as antitumoral agents: biological evaluation and structure-activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.32 | 4.91 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL397027 | — | — | 1 | 4.91 |
| CHEMBL7976 | CHALCONE | — | 1 | 4.38 |
| CHEMBL105496 | 4-METHOXY CHALCONE | — | 1 | 4.28 |
| CHEMBL241862 | — | — | 1 | 4.17 |
| CHEMBL32147 | 2'-HYDROXYCHALCONE | — | 1 | 4.10 |
| CHEMBL389328 | — | — | 1 | 4.05 |
| CHEMBL241861 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL397027 | — | IC50 | = | 12200.0 | nM | 4.91 |
| CHEMBL7976 | CHALCONE | IC50 | = | 42000.0 | nM | 4.38 |
| CHEMBL105496 | 4-METHOXY CHALCONE | IC50 | = | 53000.0 | nM | 4.28 |
| CHEMBL241862 | — | IC50 | = | 67000.0 | nM | 4.17 |
| CHEMBL32147 | 2'-HYDROXYCHALCONE | IC50 | = | 79000.0 | nM | 4.10 |
| CHEMBL389328 | — | IC50 | = | 90000.0 | nM | 4.05 |
| CHEMBL241861 | — | IC50 | - | — | - |